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#肠道微生物#

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objectTitle=Science子刊：徐金富团队发现肠道迟缓埃格特菌衍生的代谢物损害中性粒细胞功能，从而加重细菌性肺部感染！, objectType=article, longId=866106, objectId=f3d68661067a, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/images/20250227/1e585ba7e1f145c480d84daae324a56e-zMDKcFDStGOG.jpg, objectUrl=/article/show_article.do?id=f3d68661067a, replyNumber=0, likeNumber=51, createdTime=2025-03-07, rootId=0, userName=williamhill asia 管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=威斯康星, moduleDTOList=[ModuleDTO(moduleId=f3d68661067a, moduleTitle=Science子刊：徐金富团队发现肠道迟缓埃格特菌衍生的代谢物损害中性粒细胞功能，从而加重细菌性肺部感染！, moduleType=article, hrefUrl=//www.nyrain.com/article/show_article.do?id=f3d68661067a)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2253164, encodeId=cde12253164fa, content=<a href='/topic/show?id=b1fd816e094' target=_blank style='color:#2F92EE;'>#肠道微生物#</a>不错，学习了。, objectTitle=肠道微生物, objectType=topic, longId=81670, objectId=null, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/2020910/1599728155272_4754896.jpg, objectUrl=null, replyNumber=0, likeNumber=20, createdTime=2025-02-23, rootId=0, userName=1212ad1cm87暂无昵称, userId=00332233446, projectId=1, avatar=, status=1, hasArticle=0, attachment=null, ipAttribution=吉林, moduleDTOList=null, followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=2252801, encodeId=c18d225280109, content=<a href='/topic/show?id=b1fd816e094' target=_blank style='color:#2F92EE;'>#肠道微生物#</a> 您是否想过，一种曾让医学界束手无策的病毒，竟能化身精准的"微型制药厂"？2月18日《Nature Biotechnology》的最新突破“Sustained in situ protein production and release in the mammalian gut by an engineered bacteriophage”，研究人员成功将噬菌体，这种自然界最古老的病毒杀手，改造成为肠道内的蛋白质生产大师。研究团队通过基因工程技术，让T4噬菌体在感染大肠杆菌时，像特洛伊木马般释放治疗性蛋白质，成功在小鼠模型中逆转结肠炎进程、遏制肥胖发展。这项**性技术不仅攻克了口服生物制剂（Oral Biologics）难以在消化道存活的世纪难题，更开创了利用宿主共生菌群作为"活体药物工厂"的全新治疗范式。, objectTitle=肠道微生物, objectType=topic, longId=81670, objectId=null, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/2020910/1599728155272_4754896.jpg, objectUrl=null, replyNumber=0, likeNumber=24, createdTime=2025-02-20, rootId=0, userName=yangchou, userId=88b489038, projectId=1, avatar=, status=1, hasArticle=0, attachment=null, ipAttribution=浙江省, moduleDTOList=null, followStatus=false, userIsMember=false, type=1, lengthMark=1), GetTopicListResponse(id=2252772, encodeId=ac552252e721d, content=<a href='/topic/show?id=f5d3e876276' target=_blank style='color:#2F92EE;'>#结肠炎#</a> <a href='/topic/show?id=a9d940353d8' target=_blank style='color:#2F92EE;'>#噬菌体#</a> <a href='/topic/show?id=b1fd816e094' target=_blank style='color:#2F92EE;'>#肠道微生物#</a>, objectTitle=Nature Biotechnology：借菌造药：噬菌体巧用大肠杆菌打造活体药物车间, objectType=article, longId=863860, objectId=1f8086386044, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20230610/1686337301750_5579292.jpg, objectUrl=/article/show_article.do?id=1f8086386044, replyNumber=0, likeNumber=29, createdTime=2025-02-20, rootId=0, userName=williamhill asia 管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=陕西省, moduleDTOList=[ModuleDTO(moduleId=1f8086386044, moduleTitle=Nature Biotechnology：借菌造药：噬菌体巧用大肠杆菌打造活体药物车间, moduleType=article, hrefUrl=//www.nyrain.com/article/show_article.do?id=1f8086386044)], followStatus=false, userIsMember=false, type=null, lengthMark=0)] williamhill asia 话题小助手

小小微生物，实不简单！

2020-05-29

1212ad1cm87暂无昵称 (审核中...)

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#肠道微生物# 不错，学习了。

11小时前发表于吉林

williamhill asia 管理员 (审核中...)

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#肠道微生物# #代谢物# #N-酰基脂质#

2025-06-23发表于上海

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#肠道微生物# 不错，学习了。

2025-06-22发表于吉林

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#肠道微生物# 不错，学习了。

2025-06-18

williamhill asia 管理员 (审核中...)

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#肠道微生物# #胰腺癌# #测序#

2025-06-16发表于上海

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#肠道微生物# #炎性肠病# #代谢建模#

2025-06-09发表于上海

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#肠道微生物# #运动# #个体差异#

2025-06-09发表于上海

williamhill asia 管理员 (审核中...)

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#结直肠癌# #肠道微生物#

Nature Medicine：颠覆性发现：口腔细菌竟是肠癌“共犯”？跨越癌前病变到晚期，微生物群落上演“变脸秀”！

2025-06-06发表于上海

williamhill asia 管理员 (审核中...)

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#靶点# #肠道微生物# #分子机制#

2025-05-26发表于上海

williamhill asia 管理员 (审核中...)

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#肠道微生物# #新生儿黄疸# #肝脏代谢紊乱#

BMC Pediatrics：我国学者揭示新生儿溶血性黄疸肠道微生物群与肝脏代谢紊乱的关系

2025-05-23发表于上海

williamhill asia 管理员 (审核中...)

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#肠道微生物# #化疗# #卡培他滨#

2025-05-21发表于上海

williamhill asia 管理员 (审核中...)

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#二甲双胍# #肠道微生物# #谷胱甘肽# #缺血再灌注# #铁死亡#

BMC Med.：中国学者阐明经二甲双胍治疗后肠道微生物群衍生的谷胱甘肽可缓解缺血/再灌注诱导的肠道铁死亡

2025-05-15发表于上海

williamhill asia 管理员 (审核中...)

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#肠道微生物# #肠道定植#

Cell：揭秘肠道微生物“安家落户”的79条通用遗传法则

2025-04-08发表于陕西省

williamhill asia 管理员 (审核中...)

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#疫苗# #肠道微生物# #竞争菌株#

2025-04-08发表于上海

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#肠道微生物# #苯乙酰谷氨酰胺#

研究揭秘：为什么有些人看起来就是比同龄人要更年轻？

2025-03-24发表于陕西省

williamhill asia 管理员 (审核中...)

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#细胞衰老# #肠道微生物# #代谢组学# #代谢物#

Nat Aging | 中国学者揭示肠道微生物代谢产物PAGln：加速细胞衰老的“幕后黑手”及潜在抗衰老干预靶点

2025-03-07发表于陕西省

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#支气管扩张症# #肠道微生物# #熊去氧胆酸# #牛磺酸# #肠-肺轴# #迟缓埃格特菌#

Science子刊：徐金富团队发现肠道迟缓埃格特菌衍生的代谢物损害中性粒细胞功能，从而加重细菌性肺部感染！

2025-03-07发表于威斯康星

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#肠道微生物#不错，学习了。

2025-02-23发表于吉林

yangchou (审核中...)

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全文收起 #肠道微生物# 您是否想过，一种曾让医学界束手无策的病毒，竟能化身精准的"微型制药厂"？2月18日《Nature Biotechnology》的最新突破“Sustained in situ protein production and release in the mammalian gut by an engineered bacteriophage”，研究人员成功将噬菌体，这种自然界最古老的病毒杀手，改造成为肠道内的蛋白质生产大师。研究团队通过基因工程技术，让T4噬菌体在感染大肠杆菌时，像特洛伊木马般释放治疗性蛋白质，成功在小鼠模型中逆转结肠炎进程、遏制肥胖发展。这项**性技术不仅攻克了口服生物制剂（Oral Biologics）难以在消化道存活的世纪难题，更开创了利用宿主共生菌群作为"活体药物工厂"的全新治疗范式。

2025-02-20发表于浙江省

williamhill asia 管理员 (审核中...)

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#结肠炎# #噬菌体# #肠道微生物#

Nature Biotechnology：借菌造药：噬菌体巧用大肠杆菌打造活体药物车间

2025-02-20发表于陕西省

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