HMGB1 Mediates Autophagy Dysfunction via Perturbing Beclin1-Vps34 Complex in Dopaminergic Cell Model

Huang, JS; Yang, JL; Shen, Y; Jiang, HY; Han, C; Zhang, GX; Liu, L; Xu, XY; Li, J; Lin, ZC; Xiong, NA; Zhang, ZT; Xiong, J; Wang, T

Wang, T (reprint author), Huazhong Univ Sci & Technol, Tongji Med Coll, Dept Neurosurg, Union Hosp, Wuhan, Peoples R China.

Frontiers in Molecular Neuroscience, 2017; 10 ( ):

Abstract

Parkinson's disease (PD), a progressive neurodegenerative disorder, is characterized by irreversible dopaminergic neuron loss and intra-neuronal alpha......

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