Peptide Szeto-Schiller 31 ameliorates doxorubicin-induced cardiotoxicity by inhibiting the activation of the p38 MAPK signaling pathway

Zhang, L; Feng, MW; Wang, XJ; Zhang, H; Ding, JJ; Cheng, ZJ; Qian, LM

Qian, LM (corresponding author), Shanghai Jiao Tong Univ, Tongren Hosp, Dept Cardiol, Sch Med, 1111 Xianxia Rd, Shanghai 200336, Peoples R China.; Cheng, ZJ (corresponding author), Nanjing Med Univ, Dept Cardiol, Affiliated Hosp 1, 300 Guangzhou Rd, Nanjing 210029, Jiangsu, Peoples R China.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2021; 47 (4):

Abstract

Oxidative stress serves a key role in doxorubicin (DOX)-induced cardiotoxicity. The peptide Szeto-Schiller (SS)31 is an efficacious antioxidant with t......

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