A longitudinal comparison in cynomolgus macaques of the effect of brimonidine on optic nerve neuropathy using diffusion tensor imaging magnetic resonance imaging and spectral domain optical coherence tomography

Takahashi, N; Matsunaga, N; Natsume, T; Kitazawa, C; Itani, Y; Hama, A; Hayashi, I; Shimazawa, M; Hara, H; Takamatsu, H

Hama, A (corresponding author), Hamamatsu Pharma Res Inc, Pharmacol, Kita Ku, 1-3-7 Shinmiyakoda, Hamamatsu, Shizuoka 4312103, Japan.

HELIYON, 2021; 7 (4):

Abstract

Early detection of optic neuropathy is crucial for initiating treatment that could delay or prevent visual field loss. Preclinical studies have advanc......

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