The safety and tolerability of alkaloids from Alstonia scholaris leaves in healthy Chinese volunteers: a single-centre, randomized, double-blind, placebo-controlled phase I clinical trial

Gou, ZP; Zhao, YL; Zou, LL; Wang, Y; Shu, SQ; Zhu, XH; Zheng, L; Shen, Q; Luo, Z; Miao, J; Wang, YS; Luo, XD; Feng, P

Feng, P (corresponding author), Sichuan Univ, West China Hosp, Inst Drug Clin Trials, Chengdu 610041, Peoples R China.; Luo, XD (corresponding author), Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China.; Luo, XD (corresponding author), Yunnan Univ, Sch Chem Sci & Technol, Kunming 650091, Yunnan, Peoples R China.; Luo, XD (corresponding author), Yunnan Prov Ctr Res & Dev Nat Prod, Kunming 650091, Yunnan, Peoples R China.

PHARMACEUTICAL BIOLOGY, 2021; 59 (1): 484

Abstract

Context Capsule of alkaloids from the leaf of Alstonia scholaris (L.) R.Br. (Apocynaceae) (CALAS) is a new investigational botanical drug (No. 2011L01......

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