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Med J Islam Repub Ira：牙周疾病中牙龈卟啉单胞菌的研究

2018-03-03 MedSci MedSci原创

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口腔内含有各种类型的厌氧菌，包括导致牙周炎性疾病的牙龈卟啉单胞菌。牙龈卟啉单胞菌是革兰氏阴性口腔厌氧菌，被认为是牙周病的主要致病菌。既往几项研究报道了牙周疾病患者体内牙龈卟啉单胞菌与牙周病发病机制中这种细菌的关键作用之间的关系。本研究旨在使用荟萃分析来估计这种可能性。williamhill asia 搜索了PubMed，Scopus，Google Scholar和Web of Science等数据库，以确定病例对照研究，探讨牙

口腔内含有各种类型的厌氧菌，包括导致牙周炎性疾病的牙龈卟啉单胞菌。牙龈卟啉单胞菌是革兰氏阴性口腔厌氧菌，被认为是牙周病的主要致病菌。既往几项研究报道了牙周疾病患者体内牙龈卟啉单胞菌与牙周病发病机制中这种细菌的关键作用之间的关系。本研究旨在使用荟萃分析来估计这种可能性。

williamhill asia 搜索了PubMed，Scopus，Google Scholar和Web of Science等数据库，以确定病例对照研究，探讨牙龈卟啉菌与牙周病之间的关系。本研究共纳入了从1993年到2014年不同国家发表的49份报告。计算I²（异质性指数）统计数据以检验异质性。数据采用STATA第11版进行分析。

结果，经过对选定文章的详细分析后，49个病例对照研究共5924人满足荟萃分析的纳入标准。健康对照包括2600名健康个体，平均年龄为36.56±7.45岁。牙周病组3356例，平均年龄43.62±8.35岁。牙周病患者与健康对照组牙龈卟啉单胞菌之间存在统计学差异：9.24（95％CI：5.78至14.77; P = 0.000）。换句话说，牙龈卟啉单胞菌和牙周疾病之间存在明显的关联。

通过分析本研究的结果，williamhill asia 发现牙龈卟啉菌和牙周疾病之间存在密切关联。这个结果表明需要进一步的研究来进一步评估这个问题。

原始出处：

Rafiei M, Kiani F, et al., Study of Porphyromonas gingivalis in periodontal diseases: A systematic review and meta-analysis. Med J Islam Repub Iran. 2017 Sep 12;31:62. doi: 10.18869/mjiri.31.62. eCollection 2017.

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    2018-03-25 lxg951

    #LAM#

    0

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    2018-03-05 智慧医人

    #牙龈卟啉单胞菌#

    0

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    2018-03-05 liuyong2982

    #牙周#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2057621, encodeId=721d205e621cd, content=<a href='/topic/show?id=c02b106e29a' target=_blank style='color:#2F92EE;'>#LAM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10672, encryptionId=c02b106e29a, topicName=LAM)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Sun Mar 25 19:42:00 CST 2018, time=2018-03-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1361043, encodeId=d6ed136104386, content=<a href='/topic/show?id=c1006e72663' target=_blank style='color:#2F92EE;'>#牙龈卟啉单胞菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67726, encryptionId=c1006e72663, topicName=牙龈卟啉单胞菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Mon Mar 05 07:42:00 CST 2018, time=2018-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450800, encodeId=e560145080035, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Mon Mar 05 07:42:00 CST 2018, time=2018-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1484083, encodeId=321314840835f, content=<a href='/topic/show?id=1a296e52078' target=_blank style='color:#2F92EE;'>#牙周疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67520, encryptionId=1a296e52078, topicName=牙周疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0c97946807, createdName=ms7019579240139182, createdTime=Mon Mar 05 07:42:00 CST 2018, time=2018-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608607, encodeId=582c160860ec2, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Mon Mar 05 07:42:00 CST 2018, time=2018-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=293019, encodeId=902a293019aa, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Sun Mar 04 23:18:02 CST 2018, time=2018-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=292675, encodeId=19512926e5e5, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sat Mar 03 19:11:18 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=292668, encodeId=0dd629266867, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sat Mar 03 19:06:22 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=292657, encodeId=5a6129265e49, content=好好好学习天天向上, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Mar 03 18:28:48 CST 2018, time=2018-03-03, status=1, ipAttribution=)]
    2018-03-05 ms7019579240139182

    #牙周疾病#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2057621, encodeId=721d205e621cd, content=<a href='/topic/show?id=c02b106e29a' target=_blank style='color:#2F92EE;'>#LAM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10672, encryptionId=c02b106e29a, topicName=LAM)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Sun Mar 25 19:42:00 CST 2018, time=2018-03-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1361043, encodeId=d6ed136104386, content=<a href='/topic/show?id=c1006e72663' target=_blank style='color:#2F92EE;'>#牙龈卟啉单胞菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67726, encryptionId=c1006e72663, topicName=牙龈卟啉单胞菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Mon Mar 05 07:42:00 CST 2018, time=2018-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450800, encodeId=e560145080035, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Mon Mar 05 07:42:00 CST 2018, time=2018-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1484083, encodeId=321314840835f, content=<a href='/topic/show?id=1a296e52078' target=_blank style='color:#2F92EE;'>#牙周疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67520, encryptionId=1a296e52078, topicName=牙周疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0c97946807, createdName=ms7019579240139182, createdTime=Mon Mar 05 07:42:00 CST 2018, time=2018-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608607, encodeId=582c160860ec2, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Mon Mar 05 07:42:00 CST 2018, time=2018-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=293019, encodeId=902a293019aa, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Sun Mar 04 23:18:02 CST 2018, time=2018-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=292675, encodeId=19512926e5e5, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sat Mar 03 19:11:18 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=292668, encodeId=0dd629266867, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sat Mar 03 19:06:22 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=292657, encodeId=5a6129265e49, content=好好好学习天天向上, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Mar 03 18:28:48 CST 2018, time=2018-03-03, status=1, ipAttribution=)]
    2018-03-05 ms3994565386320060

    #Med#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=2057621, encodeId=721d205e621cd, content=<a href='/topic/show?id=c02b106e29a' target=_blank style='color:#2F92EE;'>#LAM#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10672, encryptionId=c02b106e29a, topicName=LAM)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=04ce158, createdName=lxg951, createdTime=Sun Mar 25 19:42:00 CST 2018, time=2018-03-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1361043, encodeId=d6ed136104386, content=<a href='/topic/show?id=c1006e72663' target=_blank style='color:#2F92EE;'>#牙龈卟啉单胞菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=64, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67726, encryptionId=c1006e72663, topicName=牙龈卟啉单胞菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Mon Mar 05 07:42:00 CST 2018, time=2018-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450800, encodeId=e560145080035, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Mon Mar 05 07:42:00 CST 2018, time=2018-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1484083, encodeId=321314840835f, content=<a href='/topic/show?id=1a296e52078' target=_blank style='color:#2F92EE;'>#牙周疾病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67520, encryptionId=1a296e52078, topicName=牙周疾病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c0c97946807, createdName=ms7019579240139182, createdTime=Mon Mar 05 07:42:00 CST 2018, time=2018-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608607, encodeId=582c160860ec2, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Mon Mar 05 07:42:00 CST 2018, time=2018-03-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=293019, encodeId=902a293019aa, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=69, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Sun Mar 04 23:18:02 CST 2018, time=2018-03-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=292675, encodeId=19512926e5e5, content=学习了受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDicHg2ldsSNmib46PmdzpO7CQEmPjuULp1v45zPWwMYhrnXgvl3OtmUCZSQfgITWn96X9moL94nUGA/0, createdBy=28072041016, createdName=131****1460, createdTime=Sat Mar 03 19:11:18 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=292668, encodeId=0dd629266867, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6Nx0VGA4QMDzOP8oAgnV4h51EjSfehJ9QxyiaSmw8PB56BhY8KXFSxHCibXrzcy4abrzSibXQPxJ9kzrLcJyhhB8a/0, createdBy=1d3b1672603, createdName=明月清辉, createdTime=Sat Mar 03 19:06:22 CST 2018, time=2018-03-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=292657, encodeId=5a6129265e49, content=好好好学习天天向上, beContent=null, objectType=article, channel=null, level=null, likeNumber=124, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45101626056, createdName=忠诚向上, createdTime=Sat Mar 03 18:28:48 CST 2018, time=2018-03-03, status=1, ipAttribution=)]
    2018-03-04 orangesking

    好

    0

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    2018-03-03 131****1460

    学习了受益匪浅

    0

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    2018-03-03 明月清辉

    谢谢分享.学习了

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    2018-03-03 忠诚向上

    好好好学习天天向上

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