Int Forum Allergy Rhinol:11年之间中国鼻息肉慢性鼻窦炎患者的临床和组织特性变化

2018-12-13 AlexYang MedSci原创

传统上认为,中国鼻息肉慢性鼻窦炎(CRSwNP)患者要比北美和欧洲患者具有更少的嗜酸性细胞和更多的中性粒细胞炎症。然而,炎症模式可能随着时间而变化。最近,有研究人员分析了中国患者CRSwNP临床和组织特性随着时间变化的趋势情况。研究包括了2003年到2005年间的115名连续性CRSwNP患者和2014年到2016年114名连续性CRSwNP患者。研究发现,在11年研究期间,嗜酸性粒细胞在鼻息肉组

传统上认为,中国鼻息肉慢性鼻窦炎(CRSwNP)患者要比北美和欧洲患者具有更少的嗜酸性细胞和更多的中性粒细胞炎症。然而,炎症模式可能随着时间而变化。最近,有研究人员分析了中国患者CRSwNP临床和组织特性随着时间变化的趋势情况。

研究包括了2003年到2005年间的115名连续性CRSwNP患者和2014年到2016年114名连续性CRSwNP患者。研究发现,在11年研究期间,嗜酸性粒细胞在鼻息肉组之中的比例增加,中性粒细胞比例和总炎症细胞数据减少。嗜酸性CRSwNP比例在11年期间从59.1%显著的增加到了73.7%。中性粒细胞的比例和总的炎症细胞数据在鼻息肉中减少,并且在手术前使用鼻内糖皮质激素的嗜酸性CRSwNP患者在11年之间显著增加。更多的是,嗜酸性CRSwNP患者比非嗜酸性CRSwNP患者具有更好的鼻内类固醇使用顺从性,并且患有并发过敏性鼻炎和哮喘的患者比没有上述情况的患者具有更好的鼻内类固醇使用顺从性。

最后,研究人员指出,嗜酸性CRSwNP是东亚之前报道的一个小的亚型,最近显著性增加并且在CRSwNP亚型中凸显,表明了鼻科医生应该对该病的诊断和治疗给予更多的关注。

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    2018-12-18 orangesking

    0

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    2018-12-15 膀胱癌
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    2018-12-14 ylzr123

    认真学习,把间接经验应用到临床实践中去,然后再总结出新思路。给点赞啦

    0

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    2018-12-13 清风拂面

    谢谢分享学习

    0

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    2018-12-13 天地飞扬

    了解一下,谢谢分享!

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